Wednesday 24th April 2019

SCOPE (Skin Care in Organ Transplant Patients, Europe) Meeting

WORKSHOP
Wednesday 24th April 2019 | 09:00 - 12:30 | PETIT AMPHITHEATRE - Level 0

Chair : Deniz SECKIN (Turkey)


  • Welcome and introduction
    Deniz SECKIN (Turkey)
  • Melanoma in the context of organ transplantation: current issues and future outlooks
    Christoph HOELLER (Austria), Alexandra GEUSAU (Austria)
  • Challenges for immunotherapy of Merkel cell carcinoma in organ transplant patients (including Q&A)
    Jurgen BECKER (Germany)
  • Posttransplant Merkel cell carcinoma: what are the challenges and what does the SCOPE experience tell us?
    Carla FERRÁNDIZ-PULIDO (Spain)
  • Tumor board: Case 1, Case 2 and Case 3
  • Coffee break
  • Management of the posttransplant advanced and high-stage cutaneous SCC: What are the difficulties, challenges and solutions? (including Q&A)
    Chrysalyne SCHMULTS (United States)
  • Closing remarks and future perspectives
    Charlotte PROBY (United Kingdom)

Controversies in Dermato-oncology I

WORKSHOP
Wednesday 24th April 2019 | 13:30 - 14:45 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Céleste LEBBE (France), Claus GARBE (Germany), Jean-Jacques GROB (France)


  • Prevention campaign will prevent skin cancer - Yes
    Alexander STRATIGOS (Greece)
  • Prevention campaign will prevent skin cancer - No
    Claus GARBE (Germany)
  • Will lymph node surgery remain a main therapy in melanoma? - Yes
    David MORENO-RAMIREZ (Spain)
  • Will lymph node surgery remain a main therapy in melanoma? - No
    Axel HAUSCHILD (Germany)
  • Adjuvant therapy should be moved to primary melanoma stage II - Yes
    Jean-Jacques GROB (France)
  • Adjuvant therapy should be moved to primary melanoma stage II - No
    Paul LORIGAN (United Kingdom)

Controversies in Dermato-oncology II

WORKSHOP
Wednesday 24th April 2019 | 14:45 - 16:00 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Brigitte DRENO (France), Ketty PERIS (Italy), Alexander STRATIGOS (Greece)


  • We should routinely measure quality of life of advanced melanoma patients - Yes
    Jessica HASSEL (Germany)
  • We should routinely measure quality of life of advanced melanoma patients - No
    Isabelle BORGET (France)
  • Tumor mutational burden (TMB) will guide our future systemic treatments - Yes
    Selma UGUREL (Germany)
  • Tumor mutational burden (TMB) will guide our future systemic treatments - No
    Olivier MICHIELIN (Switzerland)
  • Treatment of advanced melanoma: combining or sequencing? - Combining
    Paolo ASCIERTO (Italy)
  • Treatment of advanced melanoma: combining or sequencing? - Sequencing
    Dirk SCHADENDORF (Germany)

Opening Ceremony

PLENARY SESSION
Wednesday 24th April 2019 | 17:30 - 18:00 | AMPHITHEATRE LAVOISIER - Level 1


  • Welcome address
    Céleste LEBBE (France), Claus GARBE (Germany), Abdellatif TAZI (to be confirmed)
  • New developments in occupational skin cancer: WHO disease burden project and implications for our patients
    Swen Malte JOHN (Germany)

Keynote lectures 1

PLENARY SESSION
Wednesday 24th April 2019 | 18:00 - 19:00 | AMPHITHEATRE LAVOISIER - Level 1


  • New developments in occupational skin cancer: WHO disease burden project and implications for our patients
    Swen Malte JOHN (Germany)
  • The long journey from melanocyte to melanoma
    Boris BASTIAN (United States)
  • Targeting innate immunity in cancer treatment
    Eric VIVIER (France)
  • Raising the efficacy in immunotherapy of melanoma: what are we going to achieve?
    Jennifer WARGO (United States)
Thursday 25th April 2019

Management of advanced melanoma

WORKSHOP
Thursday 25th April 2019 | 08:30 - 09:30 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Paolo ASCIERTO (Italy), Thomas GAJEWSKI (United States), Caroline ROBERT (France)


  • Combining or sequencing targeted therapy and immunotherapy
    Paolo ASCIERTO (Italy)
  • How to overcome primary and secondary resistance to immune checkpoint inhibitor
    Thomas GAJEWSKI (United States)
  • How should we evaluate our patients in the era of immunotherapy? irRECIST, irRC, iRECIST?
    Caroline ROBERT (France)

Rare skin cancers and borderline neoplasms such as MELTUMP, clinic-pathological approach

WORKSHOP
Thursday 25th April 2019 | 08:30 - 10:30 | PETIT AMPHITHEATRE - Level 0

Chair : Petr ARENBERGER (Czech Republic), Boris BASTIAN (United States), Maxime BATTISTELLA (France), Matilda Bylaitė-Bučinskienė (Lithuania), Arnaud DE LA FOUCHARDIERE (France), Judit OLAH (Hungary)


  • Adnexal Tumors
    Maxime BATTISTELLA (France)
  • MELTUMP
    Arnaud DE LA FOUCHARDIERE (France)
  • Neoplastic disorders of the nipple
    Erika VARGA (Hungary)
  • Borderline vascular tumors
    Matilda Bylaitė-Bučinskienė (Lithuania)
  • Soft tissue tumors
    Judit OLAH (Hungary)
  • Overview on rare skin tumors
    Petr ARENBERGER (Czech Republic)

Lymphoma

WORKSHOP
Thursday 25th April 2019 | 09:00 - 10:30 | ROOM 151 - Level 1

Chair : Martine BAGOT (France), Julia SCARISBRICK (United Kingdom), Rudolf STADLER (Germany)


  • Tumor clone frequency is a robust predictor of progression and survival in patients with early stage mycosis fungoides
    Adèle DE MASSON (France)
  • International landscape of therapies in CTCL, Results of the PROCLIPI Study
    Pietro QUAGLINO (Italy)
  • Therapeutic Strategies for improved management in CTCL
    Rudolf STADLER (Germany)
  • New monoclonal antibodies for the treatment of CTCL
    Martine BAGOT (France)
  • Clinical endpoints updates and considerations for future staging
    Julia SCARISBRICK (United Kingdom)
  • Management of Cutaneous B cell lymphoma
    Antonio COZZIO (Switzerland)

How to prevent Melanoma Progression in tumor-free patients of…

WORKSHOP
Thursday 25th April 2019 | 09:30 - 10:30 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Axel HAUSCHILD (Germany), Jean-Jacques GROB (France), Nicolas MEYER (France)


  • Stage II
    Jean-Jacques GROB (France)
  • Stage III
    Axel HAUSCHILD (Germany)
  • Stage IV
    Nicolas MEYER (France)

Trends in skin cancer epidemiology

WORKSHOP
Thursday 25th April 2019 | 11:00 - 12:00 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Sara GANDINI (Italy), Claus GARBE (Germany), David WHITEMAN (Australia)


  • Incidence of melanoma in Europe 1950 - 2030
    Claus GARBE (Germany)
  • Which percentage of melanoma is caused by UV radiation, and what proportion could be prevented?
    David WHITEMAN (Australia)
  • Nevi and melanoma: who, when and how?
    Sara GANDINI (Italy)
  • What do we achieve with screening examinations?
    Andreas STANG (Germany)

Biomarkers in melanoma

WORKSHOP
Thursday 25th April 2019 | 11:00 - 12:00 | PETIT AMPHITHEATRE - Level 0

Chair : John HAANEN (Netherlands), Olivier MICHIELIN (Switzerland), Selma UGUREL (Germany)


  • Biomarkers in melanoma, an overview
    Olivier MICHIELIN (Switzerland)
  • Circulating cytokines and immune related toxicity
    Jenny LEE (Austria)
  • Microbiome
    Beth HELMINK (United States)
  • Single cell RNA seq of immune infiltrates
    To be confirmed

Cases of adverse events in immuno-oncology

WORKSHOP
Thursday 25th April 2019 | 11:00 - 12:00 | ROOM 151 - Level 1

Chair : Barouyr BAROUDJIAN (France), Lucie HEINZERLING (Germany), Christoph HOELLER (Austria)


  • A case of Myositis
    Lucie HEINZERLING (Germany)
  • Myocarditis: what clinicians should know
    Dimitri ARANGALAGE (France)
  • An unusual Hematologic side effect
    Erwin STRASSER (Germany)
  • Immune related hepatitis: can we resume the treatment ?
    Olivier ROUX (France)
  • Beware of rare endocrinologic immune related adverse events
    Florence BRUNET-POSSENTI (France)

Keynote lectures 2

PLENARY SESSION
Thursday 25th April 2019 | 12:00 - 13:00 | AMPHITHEATRE LAVOISIER - Level 1


  • Where and when will melanoma incidence decrease?
    David WHITEMAN (Australia)
  • How to modulate tumor microenvironment?
    Thomas GAJEWSKI (United States)
  • Molecular resistance to targeted therapy, from bench to bedside
    Grant MCARTHUR (Australia)

Prevention and skin cancer screening

WORKSHOP
Thursday 25th April 2019 | 14:00 - 15:00 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Véronique DEL MARMOL (Belgium), Ana Maria FORSEA (Romania), Eduardo NAGORE (Spain)


  • UVR and cellular damage: implications for skin cancer prevention
    Amaya VIROS (United Kingdom)
  • Melanoma risk and sunbeds use – time to close the debate
    Mariano SUPPA (Belgium)
  • Prevention according to different clinical profile
    Eduardo NAGORE (Spain)
  • Skin cancer Chemoprevention - current evidence
    Ana Maria FORSEA (Romania)

Actinic keratosis and field cancerisation

WORKSHOP
Thursday 25th April 2019 | 14:00 - 15:00 | ROOM 151 - Level 1

Chair : Ketty PERIS (Italy), Eggert STOCKFLETH (Germany), Nicole KELLENERS-SMEETS (Netherlands)


  • Biology of AK
    Eggert STOCKFLETH (Germany)
  • Diagnosis of AK
    Caterina LONGO
  • Field directed treatments
    Nicole KELLENERS-SMEETS (Netherlands)
  • AK treatment in organ transplant recipients
    Ketty PERIS (Italy)

Free communications 1

FREE COMMUNICATIONS
Thursday 25th April 2019 | 14:00 - 15:00 | PETIT AMPHITHEATRE - Level 0

Chair : Sophie DALAC-RAT (France), Lionel LARUE (France), Charlotte PROBY (United Kingdom), Dimitris SGOUROS (Greece)

Non-surgical local tumor treatment: act locally, but think distant

WORKSHOP
Thursday 25th April 2019 | 16:30 - 18:00 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Christoph HOELLER (Austria), Ricardo VIEIRA (Portugal), Philippe SAIAG (France)


  • Radiotherapy
    Philippe SAIAG (France)
  • Intralesional injections
    Christoph HOELLER (Austria)
  • Other local treatments
    Ricardo VIEIRA (Portugal)

Brain metastases

WORKSHOP
Thursday 25th April 2019 | 16:30 - 18:00 | ROOM 151 - Level 1

Chair : Emilie LE RHUN (France), Friedegund MEIER (Germany), Hussein TAWBI (United States)


  • Diagnosis and local treatment of CNS metastasis: surgery and radiotherapy
    Michael WELLER (Switzerland)
  • Targeted therapy alone or in combination with RT in melanoma CNS metastases
    Friedegund MEIER (Germany)
  • Immunotherapy alone or in combination with RT in melanoma CNS metastases
    Hussein TAWBI (United States)
  • Challenges in the design of CNS metastases trials
    Emilie LE RHUN (France)

Free communications 2

FREE COMMUNICATIONS
Thursday 25th April 2019 | 16:30 - 18:00 | PETIT AMPHITHEATRE - Level 0

Chair : Stéphane DALLE (France), Helen GOGAS (Greece), Janice MEHNERT (United States)

Friday 26th April 2019

Neoadjuvant therapy

WORKSHOP
Friday 26th April 2019 | 08:30 - 09:30 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Christian BLANK (Netherlands), James LARKIN (United Kingdom), Peter MOHR (Germany)


  • Neoadjuvant immunotherapy in melanoma
    Christian BLANK (Netherlands)
  • Neoadjuvant targeted therapy in melanoma
    Peter MOHR (Germany)
  • Neoadjuvant therapy and lessons from other tumor types and lessons to learn from former neoadjuvant trials in melanoma
    James LARKIN (United Kingdom)

Dermoscopy and confocal microscopy

WORKSHOP
Friday 26th April 2019 | 08:30 - 09:30 | ROOM 151 - Level 1

Chair : Giovanni PELLACANI (Italy), Luc THOMAS (France), Iris ZALAUDEK (Austria)


  • How dermoscopy improves differential diagnosis of melanoma
    Luc THOMAS (France)
  • How confocal microscopy improves management decisions
    Giovanni PELLACANI (Italy)
  • When instruments are not enough, clinical clues are needed
    Aimilios LALLAS (Greece)
  • Questions & Answers

The role of skin cancer centers: clinical care, quality assurance, data banking, teaching, research and innovation...

WORKSHOP
Friday 26th April 2019 | 08:30 - 10:30 | PETIT AMPHITHEATRE - Level 0

Chair : Claus GARBE (Germany), Lidija KANDOLF-SEKULOVIC (Serbia and Montenegro), Dirk SCHADENDORF (Germany), Lise BOUSSEMART (France)


  • The optimal melanoma care pathway - the European perspective
    Lidija KANDOLF-SEKULOVIC (Serbia and Montenegro)
  • The system of quality assurance of skin cancer centers in Germany
    Claus GARBE (Germany)
  • Biobanking in skin cancer centers
    Dirk SCHADENDORF (Germany)
  • Translational research in a skin cancer center: when advances in next generation sequencing serve melanoma patients' care
    Lise BOUSSEMART (France)
  • E-health data and their role in skin cancer patient management
    Thomas EIGENTLER (Germany)
  • Discussion

Practical tips for your surgical work

WORKSHOP
Friday 26th April 2019 | 09:30 - 10:30 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Florence CORGIBET (France), Roland KAUFMANN (Germany), Vernon SONDAK (United States)


  • Before and after surgical procedures
    Florence CORGIBET (France)
  • Surgical procedures for the primary tumour
    Roland KAUFMANN (Germany)
  • About the sentinel node biopsies and nodal dissections
    Vernon SONDAK (United States)

New technologies for the diagnosis of skin cancer: from computer vision (automatized diagnosis) to innovation in photonics

WORKSHOP
Friday 26th April 2019 | 09:30 - 10:30 | ROOM 151 - Level 1

Chair : Véronique DEL MARMOL (Belgium), Josep MALVEHY (Spain), Nesrine BRAHIMI (France)


  • High definition Ultrasound and skin cancer diagnosis approach
    Philippe BAHADORAN (France)
  • LC OCT : A new definition for Optical coherence tomography to diagnose skin cancer
    Mariano SUPPA (Belgium)
  • Early skin cancer detection and follow up using polarized dynamic speckle
    Xavier ORLIK (France)
  • Ex vivo confocal microscopy a new approach for skin cancer margins  
    Josep MALVEHY (Spain)

Management of advanced BCC and SCC

WORKSHOP
Friday 26th April 2019 | 10:30 - 12:00 | PETIT AMPHITHEATRE - Level 0

Chair : Nicole BASSET-SEGUIN (France), Ulrike LEITER (Germany), Michael MIGDEN (United States)


  • General principles of management of NMSC
    Alexander STRATIGOS (Greece)
  • Surgery in advanced tumors (SCC and BCC)
    David MORENO-RAMIREZ (Spain)
  • Systemic treatment of advanced BCC
    Nicole BASSET-SEGUIN (France)
  • Systemic Treatment of advanced SCC
    Ulrike LEITER (Germany)
  • Expert Panel discussion                                          
    David MORENO-RAMIREZ (Spain)
  • Expert Panel discussion
    Alexander STRATIGOS (Greece)
  • Expert Panel discussion                                          
    Nicole BASSET-SEGUIN (France)
  • Expert panel discussion: Difficult to treat BCC- challenging cases
    Matilda Bylaitė-Bučinskienė (Lithuania)
  • Expert panel discussion: Difficult to treat SCC- challenging cases
    Ingrid WOLF (Austria)

New therapeutic targets in melanoma

WORKSHOP
Friday 26th April 2019 | 11:00 - 12:00 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Brigitte DRENO (France), Grant MCARTHUR (Australia), Jessica HASSEL (Germany)

Update on the skin cancers in immunosuppressed patients, on behalf of SCOPE

WORKSHOP
Friday 26th April 2019 | 11:00 - 12:00 | ROOM 151 - Level 1

Chair : Emilie DUCROUX (France), Catherine HARWOOD (United Kingdom), Deniz SECKIN (Turkey)


  • Introduction
    Deniz SECKIN (Turkey)
  • What is new in the pathogenesis and treatment of posttransplant Kaposi's sarcoma?
    Stéphane BARETE (France)
  • The role and therapeutic implications of HPV presence in posttransplant squamous cell carcinoma: SCOPE research update
    Jan Nico BOUWES-BAVINCK (Netherlands)
  • Skin field cancerization: Converging transcription/ epigenetic regulatory pathways of translational value
    Paolo DOTTO (Switzerland)

Keynote lectures 3

PLENARY SESSION
Friday 26th April 2019 | 12:00 - 13:00 | AMPHITHEATRE LAVOISIER - Level 1


  • Biology and therapy of Merkel cell carcinoma
    Paul NGHIEM (United States)
  • Targeting pathways in basal cell carcinoma: sonic hedgehog and beyond
    Nicole BASSET-SEGUIN (France)

What is new in melanoma biology?

WORKSHOP
Friday 26th April 2019 | 14:00 - 15:30 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Boris BASTIAN (United States), Nicolas DUMAZ (France), Amaya VIROS (United Kingdom)


  • Nongenetic mechanisms as drivers of tumor evolution and therapy resistance
    Jean-Christophe MARINE (Belgium)
  • TERT promoter mutations, telomere length and melanoma survival and risk
    Rajive KUMAR (Germany)
  • Novel roles of ROCK-Myosin II in melanoma
    Victoria SANZ-MORENO (United Kingdom)
  • Neural Crest Stemness in Melanoma
    Lukas SOMMER (Switzerland)

Virus induced cancer

WORKSHOP
Friday 26th April 2019 | 14:00 - 15:30 | ROOM 151 - Level 1

Chair : Jurgen BECKER (Germany), Nicolas DUPIN (France), Paul NGHIEM (United States)


  • Immunobiology of Merkel cell carcinoma
    Jurgen BECKER (Germany)
  • Progress and challenges in Merkel cell carcinoma management
    Paul NGHIEM (United States)
  • Update on oncogenesis and therapy for Kaposi’s sarcoma
    Nicolas DUPIN (France)

Best posters session

FREE COMMUNICATIONS
Friday 26th April 2019 | 14:00 - 15:30 | PETIT AMPHITHEATRE - Level 0

Chair : Ralf GUTZMER (Germany), Gaëlle QUEREUX (France), Henri MONTAUDIE (France), Emmanuella GUENOVA (Switzerland)

What is new in NMSC biology?

WORKSHOP
Friday 26th April 2019 | 17:00 - 18:00 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Irene LEIGH (United Kingdom), Dany NASSAR (France), Chrysalyne SCHMULTS (United States)


  • Mechanisms of Resistance to Hedgehog/Smoothened Inhibitors in BCC
    Michael MIGDEN (United States)
  • Regulation of Epithelial Mesenchymal Transition in SCC
    Dany NASSAR (France)
  • Squamous Carcinogenesis: Commonalities and Difference Across Epithelial Cell Types
    Catherine HARWOOD (United Kingdom)
  • Molecular Prediction of Recurrence and Metastasis in SCC
    Chrysalyne SCHMULTS (United States)

Genodermatoses and associated cancers

WORKSHOP
Friday 26th April 2019 | 17:00 - 18:00 | ROOM 151 - Level 1

Chair : Susanna PUIG (Spain), Pierre VABRES (France), Pierre WOLKENSTEIN (France)


  • Genetics of basal cell carcinoma
    Asma SMAHI (France)
  • Genetics of familial melanoma
    Susanna PUIG (Spain)
  • Neurofibromatosis 1 and related tumours
    Pierre WOLKENSTEIN (France)
  • Genetic disorders of the PIK3CA/PTEN/MTOR pathway
    Pierre VABRES (France)

Free communications 3

FREE COMMUNICATIONS
Friday 26th April 2019 | 17:00 - 18:30 | PETIT AMPHITHEATRE - Level 0

Chair : Véronique BATAILLE (United Kingdom), Julie DELYON (France), Caroline GAUDY (France), Emmanuella GUENOVA (Switzerland)

Saturday 27th April 2019

Dermoscopy and confocal microscopy cases

WORKSHOP
Saturday 27th April 2019 | 08:30 - 09:30 | ROOM 151 - Level 1

Chair : Philippe BAHADORAN (France), Ralph BRAUN (Switzerland), Josep MALVEHY (Spain)


  • When confocal is of help 
    Caterina LONGO
  • When dermoscopy is not straight forward
    Mona AMINI-ADLER (France)
  • Basal cell carcinoma (dermoscopy, OCT and confocal),
    Mariano SUPPA (Belgium)
  • Pre- and intra-operative use of non-invasive techniques
    Susanna PUIG (Spain)

Interactive cases: management of difficult to treat carcinomas

WORKSHOP
Saturday 27th April 2019 | 08:30 - 11:00 | AMPHITHEATRE LAVOISIER - Level 1

Chair : Jean-Jacques GROB (France), Eve MAUBEC (France), Chrysalyne SCHMULTS (United States), Victor FARRICHA (Portugal)


  • Advanced SCC arising in hidradenitis suppurativa
    Eve MAUBEC (France)
  • Multiple scalp SCCs in a patient with chronic lymphocytic leukemia
    Chrysalyne SCHMULTS (United States)
  • Rapid growth of SCC while on JAK inhibitor for myelofibrosis
    Victor FARRICHA (Portugal)
  • What is a difficult to treat BCC?”
    Jean-Jacques GROB (France)
  • A young patient with sarcoidosis and voriconazole-induced locally advanced SCC
    Eve MAUBEC (France)
  • A renal transplant patient with multiply recurrent SCC. Is anti PD-1 treatment ever appropriate in transplant patients
    Chrysalyne SCHMULTS (United States)

Dermoscopy and confocal microscopy cases

WORKSHOP
Saturday 27th April 2019 | 09:30 - 10:30 | ROOM 151 - Level 1

Chair : Harald KITTLER (Austria), Aimilios LALLAS (Greece), Iris ZALAUDEK (Austria)


  • When dermoscopy is straight forward
    Aimilios LALLAS (Greece)
  • When dermoscopy is not straight forward
    Harald KITTLER (Austria)
  • When confocal is of help
    Caterina LONGO
  • Pre- and intra-operative use of non-invasive techniques
    Susanna PUIG (Spain)

Keynote lectures 4

PLENARY SESSION
Saturday 27th April 2019 | 11:30 - 12:30 | AMPHITHEATRE LAVOISIER - Level 1


  • What's new in non melanoma skin cancer?
    Brigitte DRENO (France)
  • What's new in melanoma?
    Olivier MICHIELIN (Switzerland)
  • What's new in cutaneous lymphoma?
    Marie BEYLOT-BARRY (France)

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